He aha te Dextromethorphan me Quinidine: Ngā Whakamahinga, te Inenga, ngā Pānga taha me ētahi atu

Ko te Dextromethorphan me te quinidine he rongoā rongoā e whakakotahi ana i ngā whakauru kaha e rua hei rongoā i tētahi āhuatanga neurological motuhake e kiia nei ko te pseudobulbar affect (PBA). He rerekē te mahi a tēnei huinga i te mahi a ia rongoā i runga i a ia anō, e hanga ana i tētahi huarahi rongoā ahurei mō te hunga e pā ana ki ngā wāhanga ohorere, kore e taea te whakahaere o te kata, te tangi rānei, kāore e ōrite ana ki te āhua o ō rātou ngākau.

Mēnā kua tohua tēnei rongoā ki a koe, ki tētahi tangata e manaaki ana koe, kei te pā pea koe ki tētahi āhuatanga e mōhiotia ana he nui rawa, he whakama hoki. Mā te māramatanga ki te mahi a tēnei rongoā ka āwhina koe ki te whai i te māia ake mō tō mahere manaaki me te aha e tūmanako ana i te haere tonu.

He aha te Dextromethorphan me Quinidine?

Ko te Dextromethorphan me te quinidine he rongoā rongoā e whakakotahi ana i ngā rongoā rerekē e rua ki roto i tētahi kapene kotahi. Ko te ingoa waitohu mō tēnei huinga ko Nuedexta, ā, i hangaia motuhake hei rongoā i te pseudobulbar affect (PBA).

Ko te Dextromethorphan he pūhui ka mōhiotia e koe mai i ngā rongoā mare i runga i te kaute, engari i roto i tēnei huinga, he rerekē rawa te kaupapa. Ko te Quinidine he rongoā ngākau kua whakamahia mō ngā tekau tau hei rongoā i ngā manawataki ngākau kōaro. I te wā e whakakotahi ana ēnei rongoā e rua i roto i ngā inenga motuhake, ka mahi tahi rātou ki te āwhina i te whakahaere i ngā ara roro e whai wāhi ana ki te whakaatu i te kare-ā-roto.

He ahurei te huinga nā te mea ka āwhina te quinidine i te dextromethorphan kia noho kaha ake i roto i tō tinana. Ki te kore te quinidine, ka pakaru rawa te dextromethorphan e tō ate kia whai hua mō te rongoā PBA.

He aha te Dextromethorphan me Quinidine e whakamahia ana mō?

Kua whakaaetia tēnei rongoā hei rongoā i te pānga pseudobulbar (PBA), he āhua neurological e pā ana ki ngā wā ohorere, e kore e taea te whakahaere o te kata, te tangi rānei. Ka puta ēnei wāhanga me te kore whakatūpato, ā, he maha ngā wā kaore e ōrite ki tō āhua e pūmau ana.

Ko te PBA te nuinga ka puta i roto i ngā tāngata e pā ana ki ētahi āhua neurological, i te wharanga rānei o te roro. Ka pā pea te PBA ki a koe mēnā he amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), Alzheimer's disease, Parkinson's disease, i te mea rānei kua pā koe i te whiu, i te wharanga roro rānei.

Ka taea e ngā wāhanga te whai i te whakama me te mamae, nā te mea ka puta mai i te kore. Ka kite pea koe i a koe e tangi ana i te wā o te hari, e kata ana rānei i te wā o te kōrero nui. Ka taea e ēnei urupare te whakapōrearea i ngā hononga, me te kore e pai ngā āhuatanga pāpori.

He mea nui kia mōhio he rerekē te PBA i te pouri, i ngā raruraru rānei o te ngākau. Kāore ngā whakaputanga aronganui e whakaatu i ō āhua tūturu, ā, nā te wharanga ki ngā ara roro e whakahaere ana i te whakaputanga aronganui.

Me pēhea te mahi a Dextromethorphan me Quinidine?

E mahi ana tēnei rongoā mā te whai i ngā ara roro e whakahaere ana i te whakaputanga aronganui. Ko te whakakotahitanga e whakaarohia ana he rongoā kaha, ka taea te whakaiti i ngā wāhanga PBA i te wā e whakamahia ana i te wā tonu.

E pā ana te Dextromethorphan ki ētahi matū roro e kīia ana ko te neurotransmitters, ina koa ko ērā e pā ana ki ngā ara roro e whakahaere ana i te tangi me te kata. Ka āwhina i te whakapūmau i ēnei ara kia kore ai e puta i te kore tika.

He mahi tautoko a Quinidine mā te aukati i te enzyme i tō ate e wawahi ana i te dextromethorphan i te wā tere. Ka āhei tēnei i te dextromethorphan kia noho kaha i roto i tō pūnaha mō te wā roa kia whai hua mō te rongoā PBA.

E kore te rongoā e whakaora i te āhua o te pūnaha io e pā ana ki tō PBA, engari ka taea e ia te whakaiti i te auau me te kaha o ngā wā e kata ana, e tangi ana rānei koe i te kore e taea te whakahaere. He tokomaha ngā tāngata e kite ana i ngā whakapainga i roto i ngā wiki tuatahi o te rongoā.

Me pēhea taku tango i te Dextromethorphan me te Quinidine?

Me tango e koe tēnei rongoā i te mea e whakaritea ana e tō tākuta, te tikanga e rua ngā wā i te rā, me te kai, me te kore rānei. Ko te horopeta tīmata paerewa ko te tikanga kotahi te kāpuhi ia 12 hāora, engari ka taea e tō tākuta te whakatika i tēnei i runga i te āhua o tō urupare ki te rongoā.

Ka taea e koe te tango i ngā kāpuhi me te wai, te miraka, te wai rānei. Kāore he whakaritenga motuhake kia tangohia me te kai, engari ki te pā mai te puku, ka āwhina pea te tango me te kai māmā, te paramanawa rānei.

Whakamātauria ki te tango i ō horopeta i ngā wā kotahi i ia rā kia mau tonu te taumata o te rongoā i roto i tō pūnaha. Ka taea e te whakatakoto whakamaharatanga waea, te whakamahi rānei i te kaiwhakarite pire te āwhina i a koe kia rite tonu ki tō hōtaka horopeta.

Kaua e kuru, e ngaungau, e whakatuwhera rānei i ngā kāpuhi. I hangaia kia tukuna te rongoā i roto i te huarahi motuhake, ā, ko te whakarerekē i te kāpuhi ka pā ki te pai o te mahi o te rongoā, ka whakanui rānei i tō tūponotanga ki ngā pānga taha.

Kia pēhea te roa o taku tango i te Dextromethorphan me te Quinidine?

He rerekē te roa o te rongoā i runga i tō āhuatanga takitahi me te pai o tō urupare ki te rongoā. He tokomaha ngā tāngata e hiahia ana ki te tango i te wā roa kia mau tonu te whakahaere i ā rātou tohumate PBA.

Ka hiahia pea tō tākuta ki te kite i a koe i ngā wā katoa i ngā marama tuatahi o te rongoā kia aroturuki i te pai o te mahi o te rongoā me te tirotiro mō ngā pānga taha. Ka taea e rātou te whakatika i tō horopeta, i te wā rānei i runga i tō urupare.

E kite ana ētahi tāngata i ngā whakapainga i ā rātou wā PBA i roto i ngā wiki tuatahi, i ētahi atu rānei ka hiahiatia ētahi marama kia pā mai ngā painga katoa. Ko te mea nui kia manawanui me te rite tonu ki te tango i te rongoā i te mea e whakaritea ana.

Kaua e mutu te tango i tēnei rongoā ohorere me te kore e kōrero tuatahi ki tō tākuta. Akene ka hiahia rātou ki te whakaiti i tō horopeta i te wā, hei ārai i ngā pānga o te tangohanga, i te hokinga mai rānei o ngā tohumate PBA.

He aha ngā pānga taha o te Dextromethorphan me te Quinidine?

Pērā i ngā rongoā katoa, ka taea e te dextromethorphan me te quinidine te pānga taha, ahakoa kāore e pā ana ki te katoa. Mā te māramatanga ki ngā mea e tūmanakohia ana ka āwhina koe ki te pūmau ake, me te mōhio ki te wā ki te whakapā atu ki tō kaiwhakarato hauora.

Ko ngā pānga taha noa he ngawari noa iho, ā, he maha ngā wā ka pai ake i te wā e whakatikatika ana tō tinana ki te rongoā i ngā wiki tuatahi o te maimoatanga.

Ngā pānga taha noa ka pā ki a koe:

• Te korere, te tūtae rānei
• Te whanoke, te mōrearea rānei
• Te whakapairuaki, te pōpō rānei o te puku
• Te pūhi i ō ringa, waewae, rekereke rānei
• Te ngoikore, te ngenge rānei
• Te mare, ngā tohumate rānei o te manawa
• Ngā mate i te ara mimi

Ko ēnei pānga taha noa he ngawari ki te whakahaere, ā, he maha ngā wā ka iti haere i te wā. Heoi anō, me whakapā atu koe ki tō tākuta mēnā ka pōuri rātou, ka raru rānei i ō mahi o ia rā.

He pānga taha anō he iti noa iho engari he nui ake te kino, e hiahia ana kia āwhina tonu mai te tākuta. Ahakoa he onge ēnei, he mea nui kia mōhio koe ki a rātou.

Ngā pānga taha nui e hiahia ana kia āwhina tonu mai te tākuta:

• Ngā raruraru o te manawa, te ngākau rānei e pōrearea ana
• Te whanoke nui, te ngaro rānei
• Ngā tauhohenga pānga mate pērā i te pūhi, te mōmiti, te uaua rānei ki te manawa
• Te whakapairuaki nui, te ruaki, te korere rānei
• Te toto rere ke, te pā rānei
• Te rangirua, ngā huringa rānei i te āhua hinengaro
• Te ngoikore nui o te uaua

Mēnā ka pā ki a koe ēnei pānga taha nui, whakapā atu tonu ki tō tākuta, rapu rānei i te āwhina hauora ohorere. Ko tō haumaru te mea nui, ā, he pai te whakatikatika o ngā kaiwhakarato hauora ki te āwhina i te whakahaere i ngā tohumate e pā ana.

Ko wai e kore e tango i te Dextromethorphan me te Quinidine?

Kāore tēnei rongoā i te haumaru mō te katoa, ā, ka āta tirohia e tō tākuta tō hītori hauora i mua i te whakahau. Ko ētahi āhuatanga hauora me ngā rongoā ka kore e tika, ka mōrearea rānei tēnei rongoā.

Kāore koe e tango i tēnei rongoā mēnā he āhuatanga tō ngākau, ina koa ko ētahi momo o te manawataki ngākau kōaro, te aukati ngākau rānei. Ka pā te wāhanga quinidine ki te pūnaha hiko o tō ngākau, nō reira ka hiahia tō tākuta ki te tirotiro i tō manawataki ngākau i mua i te tīmatanga o te rongoā.

Kāore pea te hunga e mate ana i te ate, i te tākihi rānei, e kaha ki te tango i tēnei rongoā i runga i te haumaru. E hiahia ana tō tinana ki te mahi ate me te tākihi hauora hei tukatuka tika i te rongoā, ā, ko te ngoikore o te mahi okana ka arahi ki ngā taumata mōrearea e pūtake ana i roto i tō pūnaha.

Mēnā kei te tango koe i ētahi atu rongoā, kāore pea tēnei huinga i te tika mōu. Kei roto i tēnei ko ētahi rongoā anti-depressant, ngā rongoā whakaheke toto, me ētahi atu rongoā ngākau ka pā mōrearea ki te dextromethorphan me te quinidine.

Me mōhio anō tō tākuta mēnā he hītori tō mate toto, te kore taurite o te hiko, mēnā rānei kei te hapū koe, kei te whakamahere rānei koe kia hapū. Kāore anō kia tino whakatauria te haumaru o tēnei rongoā i te wā e hapū ana.

Ingoa Waitohu o te Dextromethorphan me te Quinidine

Ko te ingoa waitohu mō tēnei rongoā huinga ko Nuedexta. Koinei anake te waitohu dextromethorphan me te quinidine i whakaaetia e te FDA e wātea ana i te United States.

He mea hanga a Nuedexta e Avanir Pharmaceuticals, ā, ka tae mai i roto i ngā kāpene kei roto 20 mg o te dextromethorphan me te 10 mg o te quinidine. I hangaia ia kāpene hei whakarato i te ōwehenga tika o ēnei rongoā e rua e hiahiatia ana mō te rongoā PBA whai hua.

I etahi wa ka kite pea koe i tēnei rongoā e kīia ana e tōna ingoa whānui, engari i tēnei wā, kāore he momo whānui e wātea ana. Ko te tikanga tēnei ka whiwhi koe i te ingoa waitohu Nuedexta i te wā e whakakiia ana tō rongoā.

Ka tae mai te rongoā i roto i ngā pounamu kei roto 60, 30 rānei ngā kāpene, i runga i tō rongoā me te inihua. Ka taea e tō kai rongoā te āwhina i a koe ki te mārama ki tō rongoā motuhake me te whakautu i ngā pātai mō te rongoā e whiwhi ana koe.

Ngā Kōwhiringa kē mō te Dextromethorphan me te Quinidine

I tēnei wā, ko te dextromethorphan me te quinidine anake te rongoā kua whakaaetia e te FDA mō te rongoa i te pānga pseudobulbar. Heoi anō, ka whakaaro pea tō tākuta ki ētahi atu huarahi mēnā kāore tēnei rongoā e tika ana mōu, kāore rānei e whai hua ana.

Ka tohutohu pea ētahi tākuta i ētahi rongoā anti-depressant i waho o te tapanga hei āwhina i ngā tohumate o te PBA. Kua whakaatu ngā rongoā anti-depressant tricyclic pēnei i te amitriptyline, i ngā aukati reuptake serotonin whiriwhiri (SSRIs) rānei i ētahi painga i roto i ngā rangahau haumanu, ahakoa kāore i whakaaetia mō te rongoa PBA.

Ka whai hua anō ngā huarahi kāore i te rongoā hei rongoā tāpiri. Ka taea e te rongoā kōrero, te tohutohu, me ngā rautaki whakawhiti te āwhina i a koe ki te whakahaere i ngā wero pāpori me te kare-ā-roto e puta mai ana i ngā wāhanga PBA.

Ko te mahi tahi me te neurologist, te psychiatrist rānei, he wheako ki te PBA, ka āwhina i a koe ki te tūhura i ngā kōwhiringa katoa e wātea ana. Ka taea e rātou te āwhina i a koe ki te whakatau i ngā painga me ngā tūponotanga o ngā huarahi rerekē i runga i tō āhuatanga motuhake me ētahi atu āhuatanga hauora.

Ko te mea nui ko te mahi tahi me tō rōpū hauora ki te kimi i te huarahi rongoā e pai ana mōu. Kaua e whakaroa ki te pātai pātai, ki te whakaputa rānei i ngā āwangawanga mō tō mahere rongoā.

He Pai Anei te Dextromethorphan me te Quinidine i Ētahi Atu Rongoā PBA?

Ko te dextromethorphan me te quinidine te rongoā paerewa koura mō te pānga pseudobulbar i tēnei wā, nā te mea koinei anake te rongoā i whakaaetia e te FDA mō tēnei āhuatanga. Kua whakaatu ngā rangahau haumanu he nui ake te whai hua i te placebo i te whakaiti i ngā wāhanga PBA.

Ki te whakataurite ki ngā rongoā kāore i te tapaina, pērā i ngā rongoā anti-depressant, kua rangahaua motuhake tēnei huinga, ā, kua whakamatauria he whai hua mō te PBA. I whakaatu ngā whakamātau haumanu tata ki te 85% o ngā tāngata e tango ana i te rongoā i kite i te whakapai ake i ngā tohumate PBA.

Ko te painga o te whai rongoā kua whakaaetia e te FDA ko te mea ka taea e koe te whai māia mō tōna haumaru me tōna whai huatanga. Kua pā te rongoā i ngā whakamātau tino kaha mō te PBA, kāore i rite ki ētahi atu rongoā e whakamahia ana i waho o te tapanga.

Heoi, "pai ake" e whakawhirinaki ana ki tō āhuatanga takitahi. Ka pai pea ētahi tāngata ki ngā rongoā kē, ina koa kei a rātou ētahi atu āhuatanga e kore ai e tika te dextromethorphan me te quinidine mō rātou.

Ka taea e tō tākuta te āwhina i a koe ki te mārama ki te whakataurite o tēnei rongoā ki ētahi atu kōwhiringa i runga i tō kōtaha hauora motuhake, ētahi atu rongoā e tango ana koe, me ō whāinga rongoā.

Ngā Pātai Auau mō te Dextromethorphan me te Quinidine

Q1. He Haumaru te Dextromethorphan me te Quinidine mō te Mate Ngākau?

Me whakaaro nui tēnei rongoā mēnā he mate ngākau tō, ina koa ētahi momo o ngā manawataki ngākau kōaro. Ka taea e te wāhanga quinidine te pā ki te pūnaha hiko o tō ngākau, he mea raruraru pea mō ētahi āhuatanga ngākau.

Ka hiahia pea tō tākuta ki te mahi i te electrocardiogram (ECG) i mua i te tīmatanga o te rongoā ki te tirotiro i tō manawataki ngākau. Ka arotake hoki rātou i tō momo motuhake o te mate ngākau ki te whakatau mēnā e tika ana tēnei rongoā mōu.

Mena he hītori tō tōtā o ngā raruraru ngākau, kaua e whakaaro he kore haumaru noa tēnei rongoā mōu. He maha ngā tāngata e pā ana ki te ngākau ka taea te tango i te rongoā nei me te mātakitaki tika. Ka taea e tō tākuta ngākau me te tākuta whakahau rongoā te mahi tahi kia mōhio ai koe kei te haumaru.

Q2. Me Pēhea Taku Mahi Mēnā I Tango Au i te Nui Rawa o te Dextromethorphan me te Quinidine?

Mēnā i tango koe i te nui ake i tō horopeta i whakahaua, whakapā atu ki tō tākuta, ki te pūtau whakahaere paitini rānei i te wā tonu. Ko te tango i te nui rawa o tēnei rongoā ka mōrearea, inā rā te pānga o te wāhanga quinidine ki tō ngākau.

Ngā tohu o te horopeta nui pea ko te whanoke nui, te ngaro o te mahara, te ngākau pōrearea, te whakapairuaki, te ruaki, te rangirua rānei. Mēnā ka pā tētahi o ēnei tohumate ki a koe i muri i te tango i te rongoā atu, rapua te manaakitanga hauora ohorere i te wā tonu.

Kaua e ngana ki te "whakatika" i te horopeta nui mā te karo i tō horopeta e whai ake nei. Engari, whai i ngā tohutohu a tō kaiwhakarato hauora, te pūtau whakahaere paitini rānei mō te wā hei tīmata anō i tō hōtaka horopeta noa.

Q3. Me Pēhea Taku Mahi Mēnā I Ngaro Au i tētahi Horopeta o te Dextromethorphan me te Quinidine?

Mēnā i ngaro koe i tētahi horopeta, tangohia i te wā tonu ka mahara koe, ki te kore e tata ana te wā mō tō horopeta e whai ake nei. I tērā wā, karo i te horopeta i ngaro, ka haere tonu ki tō hōtaka horopeta noa.

Kaua rawa e tango i ngā horopeta e rua i te wā kotahi hei whakatika i tētahi horopeta i ngaro. Ka piki ake pea tō tūponotanga ki ngā pānga taha, inā rā ngā raruraru manawataki ngākau mai i te nui rawa o te quinidine i te wā kotahi.

Mēnā he maha ngā wā ka wareware koe i ngā horopeta, whakaarohia te whakatakoto i ngā whakamārama waea, te whakamahi rānei i tētahi kaiwhakarite pire hei āwhina i a koe kia mau tonu. He mea nui te horopeta tonu mō te pupuri i te mana whakahaere o ō tohumate PBA.

Q4. Āhea Au e Kati ai te Tango i te Dextromethorphan me te Quinidine?

Kaua rawa koe e kati i te tango i tēnei rongoā me te kore e kōrero ki tō tākuta i te tuatahi. Ko te PBA te tikanga he āhuatanga mau tonu, ā, ko te whakamutu i te rongoā te tikanga ka hoki mai ō tohumate.

Ka whakaaro pea tō tākuta ki te whakaiti, ki te whakamutu rānei i te rongoā mena ka pai ake tō āhuatanga neurological, ki te pā mai ngā pānga taha e kore e taea te whakawhiti, ki te kore rānei e haumaru te haere tonu o te rongoā i ētahi atu āhuatanga hauora.

Mēnā me whakamutu e koe te tango i te rongoā, ka tohutohu pea tō tākuta kia whakaitihia tō horopeta i te wā, kaua e whakamutu ohorere. Mā tēnei e ārai ngā pānga tangohanga, e āhei ai te aroturuki i ō tohumate PBA.

Q5. Ka taea e au te inu waipiro i te wā e tango ana i te Dextromethorphan me te Quinidine?

Me karo koe i te waipiro, me whakaiti rānei i te waipiro i te wā e tango ana i tēnei rongoā. Ka taea e te waipiro te whakanui i ngā pānga whakangā o te dextromethorphan, ā, ka pā pea ki tō manawa, he mea kino pea tēnei ina honoa ki te quinidine.

Mēnā ka whiriwhiria e koe te inu waipiro i ētahi wā, kōrero ki tō tākuta mō ngā rohe haumaru i runga i tō āhuatanga hauora. Ka taea e rātou te whakarato aratohu e pā ana ki tō āhuatanga me ētahi atu rongoā e tango ana koe.

Kia mahara, ka taea hoki e te waipiro te whakanui i ētahi āhuatanga neurological, ā, ka uaua pea te whakahaere i ō tohumate PBA. Ka pai ake pea tō hauora me te whakahaere tohumate me te iti o te waipiro.