He aha te Infliximab: Ngā Whakamahinga, te Inenga, ngā Pānga taha, me ētahi atu mea

He rongoā kaha te Infliximab e āwhina ana ki te whakamārie i tō pūnaha ārai mate i te wā e whakaeke ana i tō tinana. Ka tukuna mā te IV (intravenous) i roto i te hōhipera, i te whare haumanu rānei, i reira ka taea e ngā tākuta te mātakitaki i a koe i te wā o te rongoā.

No tētahi rōpū e kiia nei ko te biologics tēnei rongoā, he mea hanga mai i ngā pūtau ora, kaua i ngā matū. Whakaarohia te infliximab hei āwhina whāinga e aukati ana i ngā tohu motuhake i roto i tō pūnaha ārai mate e pā ana ki te mumura me te kino o te kiko.

He aha te Infliximab e whakamahia ana?

Ka rongoā te Infliximab i ētahi āhuatanga ārai-aunoa e whakaeke hē ana tō pūnaha ārai mate i ngā wāhanga hauora o tō tinana. Ka tohua pea e tō tākuta i te wā kāore anō ētahi atu rongoā i whai hua ki te whakamāmā i ō tohumate.

Kua whakaaetia te rongoā e te FDA mō ēnei āhuatanga motuhake:

• Rheumatoid arthritis (i te wā e honoa ana ki te methotrexate)
• Te mate a Crohn me te ulcerative colitis
• Ankylosing spondylitis
• Psoriatic arthritis
• Plaque psoriasis

Kei roto i ia o ēnei āhuatanga te mumura mau tonu e pā ana ki te mamae nui me te raru i ngā mahi o ia rā. Ka āwhina te Infliximab ki te whakaiti i tēnei mumura, ka taea te whakahaere pai i ngā tohumate me te whakapai ake i te kounga o te oranga.

Me pēhea te mahi a Infliximab?

Ka mahi te Infliximab mā te aukati i tētahi pūmua e kiia nei ko te tumor necrosis factor-alpha (TNF-alpha) e whai wāhi nui ana ki te mumura. I te wā e whakaputa ana tō pūnaha ārai mate i te nui rawa o te TNF-alpha, ka pā pea te pūhihi mamae me te kino o te kiko e kitea ana i ngā mate ārai-aunoa.

Mā te here ki te TNF-alpha me te aukati i tōna mahi, ka āwhina te infliximab ki te wawahi i te huringa o te mumura. Koinei te take e kiia ana he TNF blocker, he TNF inhibitor rānei.

He rongoā kaha tēnei, he rongoā e whāia ana te whāinga. Ko te tikanga, ka rahuitia mō ngā tūāhua waenga ki te kaha, i te wā kāore anō ētahi atu rongoā i whai hua. Ko te nuinga o ngā pānga ka kitea i roto i ngā wiki torutoru ki te marama i muri i te tīmatanga o te rongoā.

Me pēhea taku tango i te Infliximab?

Ka hoatu anake te Infliximab hei whakauru IV i roto i te taiao hauora pēnei i te hōhipera, te whare haumanu, te pokapū whakauru rānei. Kāore e taea e koe te tango i tēnei rongoā i te kāinga, mā te waha rānei.

Ko te tikanga whakauru e 2-3 haora te roa, ā, ka aroturukihia koe e ngā tāngata hauora puta noa. Ko te nuinga o te iwi ka whiwhi i ā rātou horopeta tuatahi e toru i ngā wiki 0, 2, me te 6, ka haere tonu me ngā whakaurunga ia 8 wiki.

I mua i ia whakaurunga, ka tirohia e tō rōpū hauora ō tohu nui me te pātai mō ō tohumate, ō āwangawanga rānei. Kāore koe e hiahia ki te nohopuku i mua i te rongoā, engari he pai ki te kai i te kai māmā me te noho wai.

Ka pai pea koe ki te kawe i tētahi pukapuka, papa, ētahi atu mahi marie rānei i te mea ka noho koe mō ētahi haora. Ka pā ētahi tāngata i te ngenge i muri i te rongoā, nā reira whakaarohia te whakarite kia haria koe e tētahi ki te kāinga.

Kia pēhea te roa e tango ana ahau i te Infliximab?

He rerekē te roa o te rongoā infliximab i runga i tō tūāhua me te pai o tō urupare ki te rongoā. Ka hiahia pea ētahi tāngata ki te rongoā mō ētahi marama, i te mea ka haere tonu ētahi mō ngā tau.

Ka arotakehia e tō tākuta te pai o te mahi a te rongoā me te mōrearea o te pānga kino. Ka whakamahia e rātou ngā whakamātautau toto, ngā rangahau whakaahua, me ō pūrongo tohumate hei whakatau i ēnei whakatau.

He mea nui kia kaua rawa e whakamutu ohorere i te infliximab me te kore e kōrero tuatahi ki tō tākuta. Ko te whakamutu ohorere ka hoki mai anō ō tohumate, i ētahi wā ka kaha ake i mua. Ka waihangahia e tō rōpū hauora tētahi mahere e tika ana mō tō tūāhua.

He aha ngā pānga kino o te Infliximab?

Pērā i ngā rongoā katoa, ka pānga ngā pānga taha ki te infliximab, ahakoa kāore te katoa e pā ana ki a rātou. Mā te māramatanga ki ngā mea hei mātakitaki ka āwhina koe kia noho haumaru me te whai hua nui mai i te rongoā.

Ngā pānga taha noa e pā ana ki te nuinga o te tangata ko:

• Te ānini me te ngenge
• Ngā mate i te ara rererangi o runga pērā i te makariri
• Te mamae o te puku, te whakapairuaki rānei
• Ngā tauhohenga i te wāhi whakauru
• Ngā mamae uaua, ngā mamae tahi rānei

Ko ēnei pānga taha he ngawari noa iho, ā, he maha ngā wā ka pai ake i te wā e urutau ana tō tinana ki te rongoā. Heoi anō, me pūrongo tonu koe i ngā tohumate hou, i ngā tohumate rānei e kino haere ana ki tō rōpū hauora.

Ko ngā pānga taha nui ake te hiahia kia tere te āwhina hauora, ahakoa he iti noa iho:

• Ngā tohu o te mate nui (te kirika, te wiri, te mare tonu, ngā tohumate pērā i te rewharewha)
• Te ngenge, te ngoikore rānei e kore e rite
• Ngā huringa kiri tae atu ki ngā tipu hou, ngā patunga rānei
• Te mamae puku tonu, ngā huringa rānei i ngā nekehanga whekau
• Te uaua ki te manawa, te mamae rānei o te uma

Nā te mea ka pānga te infliximab ki tō pūnaha ārai mate, tērā pea ka nui ake te tūponotanga ki ngā mate. Ka mātakitaki tō tākuta i a koe, ā, tērā pea ka tūtohu kia karo i ētahi kano ārai mate, i ngā wāhi kikī rānei i ngā wā o te mate.

Ko wai kāore e tika kia tango Infliximab?

Kāore te Infliximab i te haumaru mō te katoa, ā, ka āta arotake tō tākuta i tō hītori hauora i mua i te whakahau. Ko ētahi āhuatanga hauora, ko ētahi āhuatanga rānei ka kore e tika, ka mōrearea rānei tēnei rongoā.

Kāore koe e whiwhi infliximab mēnā kei a koe:

• Ngā mate kaha, ina koa te mate kohi, te hepatitis B rānei
• Te ngoikore o te ngākau (waenga ki te kaha)
• Te mate pāwera mō te infliximab, ōna wāhanga rānei
• Ētahi momo mate pukupuku, he hītori rānei mō te lymphoma

Ka whakamahi hoki tō tākuta i te tūpato anō ki te whai koe i te mate huka, i ngā raruraru ate, i te hītori rānei o ngā mate hoki mai. Ka hiahiatia pea e rātou ētahi atu whakamātautau, aroturuki rānei i mua i te tīmatanga o te rongoā.

Me whai whakaaro motuhake ki te hapū me te whāngai ū. Ahakoa ka whakamahia pea te infliximab i te wā o te hapū i ētahi āhuatanga, he mea nui kia kōrerohia ngā tūponotanga me ngā painga ki tō rōpū hauora.

Ngā Ingoa Waitohu o Infliximab

Ko te ingoa waitohu mō te infliximab ko Remicade, koinei te putanga taketake o tēnei rongoā. Ka tūtaki pea koe ki ngā putanga koiora, he rongoā tino rite tēnei e mahi ana i te ara kotahi.

Ngā ingoa koiora noa ko Inflectra, Renflexis, me Ixifi. Kua whakamatauria ēnei koiora he rite tonu te whai hua me te haumaru ki te Remicade taketake, ahakoa ka rerekē pea te inihua i waenga i ngā putanga rerekē.

Ka mahi tahi tō tākuta me te kaimātai rongoā ki te whakatau ko tēhea putanga te mea pai mōu i runga i te whai huatanga, te wātea, me ngā whakaaro utu.

Ngā Kōwhiringa kē mō Infliximab

Ki te kore te infliximab e tika ana mōu, ka mutu rānei te mahi whai hua, he maha atu ngā kōwhiringa rongoā e wātea ana. Ka taea e tō tākuta te āwhina i a koe ki te tūhura i ēnei kōwhiringa kē i runga i tō āhuatanga motuhake me te hītori hauora.

Ko ētahi atu aukati TNF ko adalimumab (Humira), etanercept (Enbrel), me certolizumab (Cimzia). E mahi ana ēnei i te ara rite ki te infliximab engari ka hoatu pea hei werohanga ka taea e koe te mahi i te kāinga.

Ko ngā koiora kore-TNF pēnei i te rituximab, tocilizumab, rānei, abatacept rānei e whāia ana ngā wāhanga rerekē o te pūnaha ārai mate. Ko ngā rongoā whakarerekē i te mate tuku iho pēnei i te methotrexate, sulfasalazine, rānei, hydroxychloroquine rānei ka waiho pea hei kōwhiringa.

Ka whakawhirinaki te kōwhiringa ki ngā āhuatanga pēnei i tō tātaritanga motuhake, ngā rongoā o mua, ngā hiahia o te oranga, me te pēhea te urupare o tō tinana ki ngā rongoā rerekē.

He Pai Anei te Infliximab i te Adalimumab?

He pai te mahi a te infliximab me te adalimumab hei aukati i te TNF, engari he rerekē ō rāua painga i runga i tō āhuatanga. Kāore tētahi i te pai ake i tētahi.

Ka tukuna te Infliximab mā te IV i ngā wiki e 8, ko te tikanga he iti ake te horopeta engari me haere ki te hōhipera. Ko te Adalimumab he werohanga-whaiaro ka tukuna ia wiki i tō kāinga, he pai ake te wātea engari he nui ake te horopeta.

Ko ētahi tāngata e pai ake ana te urupare ki tētahi rongoā i tētahi atu, ā, kāore e taea te matapae i mua. Ka taea e tō tākuta te whiriwhiri i tētahi i runga i tō āhuatanga motuhake, te kāhua o te oranga, te inihua, te hītori rānei o te rongoā i mua.

He rite te whai huatanga me ngā pānga taha o ngā rongoā e rua. Ko te whakatau i te nuinga o te wā ka heke iho ki te hiahia whaiaro mō ngā haerenga ki te hōhipera, ki ngā werohanga rānei i te kāinga.

Ngā Pātai Auau mō Infliximab

Q1. He Haumaru te Infliximab mō te hunga mate huka?

Ka taea te whakamahi i te Infliximab mō te hunga mate huka, engari me nui ake te aroturuki me ngā whakatūpato. I te mea ka pā te mate huka ki tō pūnaha ārai mate me te whakaora, ka tino mātakitaki tō tākuta i a koe mō ngā tohu o te mate.

Me whai whakamātautau toto auau koe hei aroturuki i ō taumata huka toto me te hauora whānui. He mea nui kia mau tonu te mana whakahaere i te huka toto i te wā e tango ana koe i te infliximab, i te mea ka āwhina tēnei i tō pūnaha ārai mate kia pai te mahi.

Q2. Me aha au mēnā ka whiwhi au i te nui rawa o te Infliximab?

I te mea ka tukuna te infliximab i roto i te taiao rongoā, he tino onge te nui rawa o te horopeta. Ka tino tatau, ka aroturuki e ngā tāngata ngaio hauora tō horopeta i te wā o ia whakaurunga.

Mēnā e māharahara ana koe mō te whiwhi i te horopeta hē, kaua e whakaroa ki te pātai ki tō rōpū hauora kia whakapūmau i ō mōhiohio me te horopeta i mua i te tīmatanga o te rongoā. Me tirohia tonu e rātou tō tuakiri me te arotake i tō mahere rongoā ki a koe.

Q3. Me aha au mēnā ka ngaro au i te horopeta o Infliximab?

Mēnā ka ngaro koe i tētahi whakaurunga kua whakaritea, whakapā atu ki tō kaiwhakarato hauora i te wa e taea ai ki te whakarite anō. Kaua e ngana ki te utu i tētahi horopeta i ngaro mā te whiwhi rongoā atu i muri mai.

Mā tō tākuta e whakatau te huarahi pai hei whakahoki i a koe ki te ara tika me tō mahere maimoatanga. Mā tēnei pea e whakatika te wā o tō horopeta e whai ake nei, e arotake anō rānei i tō mahere maimoatanga.

Q4. Āhea Āhei Ai Au ki te Kati te Tango Infliximab?

Ko te whakatau ki te whakamutu i te infliximab me mahi tonu me te ārahitanga a tō tākuta. Ka taea pea e ētahi tāngata te whakamutu i muri i te whakatutukitanga i te murunga roa, i te wā e hiahia ana ētahi atu ki te maimoatanga tonu.

Ka whakaaro tō tākuta i ngā āhuatanga pēnei i te pai o te whakahaere i tō āhuatanga, te roa o tō pumau, me tō tūponotanga ki te mura. Ka āta whakaiti pea rātou i tō horopeta, ka whakanui rānei i te wā i waenga i ngā whakaurunga i mua i te whakamutu katoa.

Q5. Ka Taea e Au te Whiwhi Kano Ārai Mate i te Wā e Tango ana i te Infliximab?

He haumaru te nuinga o ngā kano ārai mate i te wā e tango ana i te infliximab, engari me karo ngā kano ārai mate ora. Mā tō tākuta e arotake ngā kano ārai mate e hiahia ana koe me te wā ki te whiwhi i a rātou.

He mea tūtohu pinepine kia whakahou i ō kano ārai mate i mua i te tīmatanga o te maimoatanga infliximab. He mea nui ngā kano ārai mate noa pēnei i te werohanga rewharewha me te kano ārai mate pneumonia i te mea ka taea e te infliximab te whakanui i tō tūponotanga ki te mate.