He aha te Lasmiditan: Ngā Whakamahinga, te Inenga, ngā Pānga taha me ētahi atu

He rongoā hou a Lasmiditan i hangaia hei rongoā i ngā mamae mahunga migraine i roto i ngā pakeke. No roto i te rōpū rongoā e kīia ana ko ngā kaiwhakahohe kaiwhakawhiwhi serotonin whiriwhiri, e mahi rerekē ana i ngā rongoā migraine tuku iho mā te aro ki ngā kaiwhakawhiwhi roro motuhake e whai wāhi ana ki te mamae migraine.

E whai ana tēnei rongoā i te tūmanako mō ngā tāngata kāore anō i kite i te whakawātea i ētahi atu rongoā migraine, i te hunga rānei e kore e taea te tango i ētahi rongoā migraine nā te mate ngākau. Mā te māramatanga ki te mahi a lasmiditan me te aha e tūmanakohia ana ka āwhina koe ki te whakatau i ngā whakatau mō te tiaki i tō migraine.

He aha te Lasmiditan?

He rongoā a Lasmiditan e rongoā ana i ngā whakaeke migraine koi me te kore aura i roto i ngā pakeke. Kāore i rite ki ētahi rongoā migraine tawhito, kāore e pā ana ki ngā oko toto i tō ngākau, he kōwhiringa haumaru ake mō ngā tāngata e whai ana i ētahi mate cardiovascular.

E mahi ana te rongoā mā te whakahohe i ngā kaiwhakawhiwhi serotonin motuhake i tō roro e kīia ana ko ngā kaiwhakawhiwhi 5-HT1F. He wāhi nui tēnei i roto i ngā ara mamae migraine. Ki te herea a lasmiditan ki ēnei kaiwhakawhiwhi, ka āwhina i te whakaiti i te mumura me ngā tohu mamae e hanga ana i ō tohu migraine.

Ka mōhio pea koe ki a lasmiditan mā tōna ingoa waitohu, Reyvow. I whakaaetia e te FDA i te tau 2019 hei rongoā tuatahi i roto i tōna rōpū, e tohu ana i te ahunga whakamua nui i roto i ngā kōwhiringa rongoā migraine.

He aha te Lasmiditan e whakamahia ana mō?

Ka whakamahia motuhake a Lasmiditan ki te rongoā i ngā whakaeke migraine koi i roto i ngā pakeke. Ko te tikanga tēnei i hangaia hei aukati i te migraine kua tīmata kē, kaua ki te ārai i ngā migraine a muri ake nei.

Ka tohutohu pea tō tākuta i te lasmiditan mēnā ka pā koe i ngā mamae mahunga migraine ngawari ki te kaha e pā ana ki ō mahi o ia rā. Ka āwhina i te mamae mahunga e pupuhi ana, te whakapairuaki, me te tairongo ki te mārama me te oro e haere tahi ana me ngā migraine.

He mea nui tēnei rongoā mō te hunga e mate ana i te mate ngākau, te pēhanga toto tiketike, ētahi atu āhuatanga rānei o te punaha cardiovascular e kore ai e haumaru ngā rongoā triptan tuku iho. He kōwhiringa anō hoki mō te hunga i whakamātau i ētahi atu rongoā migraine kāore i whai hua, i pā rānei ki ngā pānga taha e raruraru ana.

Me pēhea te mahi a Lasmiditan?

Ka mahi a Lasmiditan mā te aro ki ngā kaiwhakawhiwhi serotonin motuhake i tō roro e kīia ana ko ngā kaiwhakawhiwhi 5-HT1F. Ka tīmata te migraine, ka kaha rawa ētahi ara mamae, ka tukuna ngā tohu mamae kaha puta noa i tō upoko, ka pā mai ētahi atu tohu pēnei i te whakapairuaki.

Mā te here ki ēnei kaiwhakawhiwhi, ka āwhina a lasmiditan ki te whakamārie i ngā ara io kaha rawa e whakaputa ana i te mamae migraine. Ka whakaiti hoki i te mumura i roto i te kiko roro e whai wāhi ana ki ngā tohu migraine. Mā tēnei huarahi whāinga ka āwhina ki te aukati i te tukanga migraine i te tīmatanga.

E kiia ana he kaha ngāwari te rongoā, ā, ka tīmata te mahi i roto i ngā hāora e rua i muri i te tango. Kāore i rite ki ētahi rongoā migraine e whāiti ana i ngā oko toto, kāore a lasmiditan e pā nui ki tō punaha cardiovascular, e haumaru ana mō te hunga e mate ana i te mate ngākau.

Me pēhea taku tango i te Lasmiditan?

Tangohia te lasmiditan i runga i te tohutohu a tō tākuta, te tikanga he horopeta kotahi i te wā e pōturi ana te migraine. Ka taea e koe te tango me te kore kai rānei, ahakoa te tango me te kai ka āwhina pea ki te whakaiti i te puku puku mēnā ka whakapairuaki koe.

Horomia te papa katoa me te karaihe wai katoa. Kaua e kuru, e whati, e ngaungau rānei i te papa, nā te mea ka pā tēnei ki te āhua o te rongoā e ngongo ana. Ko te horopeta tīmata noa ko te 50mg, ahakoa ka tohutohu pea tō tākuta i te 100mg mēnā e tika ana.

He mea nui kia tango i te lasmiditan i te wa e mohio ana koe kei te timata nga tohu o te migraine. He pai ake te mahi a te rongoa ina tangohia wawe i te wa o te migraine, i mua i te kaha o te mamae. Ki te kore e pai ake to migraine i muri i nga haora e rua, kaua e tango i te horopeta tuarua me te kore e korero tuatahi ki to taakuta.

Kia Pehea Te Roa E Tango Ai Au i te Lasmiditan?

I hangaia te Lasmiditan mo te whakamahi mo te wa poto ki te rongoa i nga whakaeke migraine takitahi, kaua mo te aukati i ia ra mo te wa roa. Me tango noa e koe i te wa e pa ana koe ki te migraine, kaua hei tikanga aukati.

Ko te tikanga ka puta te awhina o te rongoa i roto i nga haora e rua, a ka taea e ona paanga te roa ki te 24 haora. Kaua koe e tango i te horopeta nui atu i te kotahi i roto i te 24-haora, ki te kore e tohutohuhia e to taakuta. Ko te tango i te nuinga o te wa ka arahi ki te mamae o te mahunga na te nui o te rongoa.

Ki te kite koe kei te hiahia koe ki te lasmiditan neke atu i te 10 ra ia marama, korero ki to taakuta mo nga maimoatanga migraine aukati. Ko te whakamahi i nga rongoa migraine koi i nga wa katoa ka kino ake te mamae o te mahunga i te wa, no reira he mea nui kia whakamahia kia rite ki te tohutohu.

He aha nga paanga taha o te Lasmiditan?

Pērā i ngā rongoā katoa, ka taea e te lasmiditan te pānga taha, ahakoa kāore te katoa e pā ana ki a rātou. Ko nga paanga taha noa he ngawari noa iho, he wa poto, ka ngaro i te wa e wehe ana te rongoa i to punaha.

Anei nga paanga taha e tino korerohia ana ka pa ki a koe:

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• Te whanoke, te ngaro ranei
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• Te hiamoe, te ngenge ranei
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• Te whakapairuaki, te mamae puku ranei
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• Te ngoikore o te uaua, te kore ranei e pumau
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• Te ngau, te ngongo ranei i nga ringa, i nga waewae ranei
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• Waha maroke
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• Te ahua kore hono, te

  Ko ēnei pānga taha noa ka pai ake i roto i ngā hāora ruarua i te wā e tukatuka ana tō tinana i te rongoā. Ko te whanoke me te pōuri ka tino kitea, koinei te take kāore koe e pōtae waka, e whakahaere rānei i ngā mīhini mō te waru hāora i muri i te tango i te lasmiditan.

  Ko ngā pānga taha kāore i te noa engari he nui ake te kino e hiahia ana kia āwhina tonu mai i te tākuta ko:

  • Te whanoke nui, te ngaro rānei o te mahara
  • Te uaua ki te hā, te pōkae rānei o te uma
  • Te ngoikore nui o te uaua
  • Te rangirua, te ngaro rānei o te wāhi
  • Ngā tauhohenga pāwera pēnei i te pupuhi, te mōmiti, te pūhi rānei

  Mēnā ka pā ki a koe ēnei pānga taha kino, whakapā atu ki tō kaiwhakarato hauora tonu, rapu rānei i te āwhina hauora ohorere. Ahakoa he mea noa, ko ēnei tohumate ka tohu i te tauhohenga kino e hiahia ana kia rongoā wawe.

  Ko wai kāore e tika ana kia tango i te Lasmiditan?

  Kāore te Lasmiditan i te tika mō te katoa, ā, ko ētahi āhuatanga hauora, āhuatanga rānei ka kore e haumaru te whakamahi. Ka āta arotake tō tākuta i tō hītori hauora i mua i te whakahau i tēnei rongoā.

  Kāore koe e tango i te lasmiditan mēnā he mate ate nui tō, nā te mea kāore pea tō tinana e kaha ki te tukatuka i te rongoā. Ko ngā tāngata he hītori o te whiu, te whakaeke ngākau, ētahi atu āhuatanga ngākau nui rānei me karo hoki i tēnei rongoā.

  Ko ēnei ngā āhuatanga matua me ngā āhuatanga kāore i te tūtohutia te lasmiditan:

  • Te mate ate nui, te kore rānei o te ate
  • Te whiu o mua, te whakaeke ischemic transient rānei (TIA)
  • Hītori o te whakaeke ngākau, ngā raruraru rānei o te manawataki ngākau
  • Te toto tiketike kāore i te whakahaerehia
  • Te hapū, te whāngai ū rānei
  • Te tau i raro i te 18 tau
  • Ngā pāwera mō te lasmiditan, ōna kai rānei

  I tua atu, me tūpato koe mēnā he raruraru tāu ki te tākihi, e tango ana i ētahi rongoā anti-depressant, he hītori rānei tō ki te whakamahi i ngā matū kino. Ka taea te whakanui i ngā pānga whakamauri o te lasmiditan e te waipiro, e ētahi atu rānei e pōpō ana i te pūnaha io pokapū, nā reira me karo ēnei huinga.

  Ingoa Waitohu Lasmiditan

  Ka hokona te Lasmiditan i raro i te ingoa waitohu Reyvow i te United States. Ko tēnei rongoā waitohu i hangaia e Eli Lilly and Company, ā, i te tuatahi i whakaaetia e te FDA i Oketopa 2019.

  E wātea ana a Reyvow i roto i ngā kaha e rua: 50mg me te 100mg papa. Kei roto i ngā kaha e rua te whakauru kaha kotahi, te lasmiditan, engari i roto i ngā rahinga rerekē kia taea ai te horopeta whaiaro i runga i ō hiahia me te urupare ki te rongoā.

  I tēnei wā, kāore he putanga generic o te lasmiditan e wātea ana, i te mea kei te tiakina tonu te rongoā e te patent. Ko te tikanga ko Reyvow anake te waitohu e wātea ana, ka nui ake te utu i ngā rongoā migraine tawhito he momo generic.

  Ngā Kōwhiringa Lasmiditan

  Mēnā kāore te lasmiditan e pai ana mōu, kāore rānei e whai hua ana, he maha atu ngā kōwhiringa rongoā migraine e wātea ana. Ka taea e tō tākuta te āwhina i a koe ki te kimi i te kōwhiringa pai rawa atu i runga i tō hītori hauora me ō hiahia.

  Ko ngā rongoā triptan tuku iho pēnei i te sumatriptan (Imitrex), rizatriptan (Maxalt), me te zolmitriptan (Zomig) te mea e whakamātauhia ana i te tuatahi. E mahi ana ēnei rongoā mā te whāiti i ngā oko toto i roto i te roro, ā, he whai hua mō te nuinga o te tangata, ahakoa kāore i te pai mō te hunga he mate ngākau.

  Koinei ngā kāwai matua o ngā kōwhiringa rongoā migraine:

  • Triptans (sumatriptan, rizatriptan, eletriptan)
  • Ngā kaiwhakatakataka CGRP (ubrogepant, rimegepant)
  • Ngā alkaloid Ergot (dihydroergotamine)
  • Ngā rongoā anti-nausea (metoclopramide, ondansetron)
  • Ngā rongoā mamae (ibuprofen, naproxen, acetaminophen)
  • Ngā rongoā huinga (sumatriptanaproxen)

  Ko nga kōwhiringa hou pēnei i te ubrogepant (Ubrelvy) me te rimegepant (Nurtec ODT) e mahi ana i te ara rite ki te lasmiditan mā te aro ki ngā kaiwhakawhiwhi rerekē e whai wāhi ana ki te mamae migraine. Ko ēnei CGRP antagonists he pai pea hei kōwhiringa kē atu mēnā kāore e taea e koe te tango lasmiditan engari e hiahia ana koe ki tētahi kōwhiringa haumaru-ngākau.

  He Pai Anei te Lasmiditan i te Sumatriptan?

  He whai hua ngā rongoā migraine e rua, te lasmiditan me te sumatriptan, engari he rerekē te mahi me ngā painga motuhake e whakawhirinaki ana ki tō āhuatanga takitahi. Kāore tētahi i te "pai" ake i tētahi, i te mea ko te kōwhiringa pai rawa atu e whakawhirinaki ana ki tō kōtaha hauora me te urupare ki te rongoā.

  Kua roa te wā e wātea ana te Sumatriptan, ā, he nui ake te rangahau e tautoko ana i tōna whai huatanga. He maha ngā wā ka whakamātauhia tuatahi nā te mea e wātea ana i roto i ngā momo maha (papa, werohanga, rehu ihu) me ngā putanga whānui e wātea ana, e ngāwari ake ai te utu. Heoi, ka taea e te sumatriptan te whāiti i ngā oko toto, e kore ai e tika mō ngā tāngata e pā ana ki te ngākau.

  Ko te painga nui o te Lasmiditan ko tōna kōtaha haumaru mō ngā tāngata e pā ana ki te ngākau. Kāore e pā ana ki ngā oko toto i roto i te ngākau, e waiho ana hei kōwhiringa haumaru ake mēnā he mate ngākau tō, he toto tiketike, he ētahi atu tūponotanga ngākau. Ka taea hoki e ia te whakaputa i ngā mamae mahunga iti ake me te whakamahi auau.

  Ko te kōwhiringa i waenga i ēnei rongoā ka heke iho ki tō kōtaha hauora motuhake. Mēnā he mate ngākau tō, he pai ake pea te lasmiditan. Mēnā kāore ō āwangawanga ngākau, ā, he take te utu, he pai ake pea te sumatriptan.

  Ngā Pātai Auau mō Lasmiditan

  He Haumaru Anei te Lasmiditan mō ngā Tāngata e Pā ana ki te Mate Ngākau?

  Āe, e whakaarohia ana te lasmiditan he haumaru ake mō ngā tāngata e pā ana ki te mate ngākau i te rongoā migraine tuku iho pēnei i te triptans. Kāore i rite ki te triptans, kāore te lasmiditan e whāiti nui i ngā oko toto i roto i te ngākau, e whakaiti ana i te tūponotanga o ngā raruraru ngākau.

  Heoi anō, me kōrero tonu koe i tō āhuatanga ngākau ki tō tākuta i mua i te tīmatanga o te lasmiditan. Ahakoa he haumaru ake mō te nuinga o ngā tāngata whai mate ngākau, ētahi āhuatanga ngākau nui pea e kore e tika. Mā tō tākuta e arotake ō āhuatanga tūpono takitahi, ā, ka whakatau mēnā e tika ana te lasmiditan mō tō āhuatanga.

  Me Pēhea Taku Mahi Mēnā Ka Whakamahi Au i te Nui Rawa o te Lasmiditan?

  Mēnā ka inu koe i te nui rawa o te lasmiditan i te mea i whakaritea, whakapā atu ki tō tākuta, ki te pokapū whakahaere paitini tonu. Ko te inu i te nui rawa ka piki ake te tūponotanga o ngā pānga taha nui pēnei i te whanoke nui, te moe nui, te uaua rānei ki te hā.

  Kaua e ngana ki te taraiwa i a koe anō ki te tiki awhina, nā te mea ka pā te rongoā i te moe nui me te whanoke. Me tono tētahi atu ki te taraiwa i a koe ki te ruma ohorere mēnā i tūtohutia e tō kaiwhakarato hauora. Mauria mai te pounamu rongoā ki a koe kia kite te kaimahi hauora i te aha me te nui i inumia e koe.

  Ngā tohu o te horopeta nui pea ko te ngenge nui, te rangirua, te uaua ki te noho mataara, te raruraru rānei ki te ruruku. Ahakoa ka pai koe i te tīmatanga, he mea nui kia rapu awhina hauora, nā te mea kāore pea ētahi pānga e puta tonu.

  Me Pēhea Taku Mahi Mēnā Ka Ngaro Au i te Inenga o te Lasmiditan?

  Ka tangohia te Lasmiditan i te wā e pā ana te migraine ki a koe, kāore i runga i te hōtaka auau, nō reira kāore koe e taea te

  Mēnā kāore koe i te mōhio me tango rānei te lasmiditan mō te migraine kua roa e pā ana, whakapā atu ki tō tākuta mō te tohutohu. Ka taea e rātou te āwhina i a koe ki te whakatau mēnā he pai tonu te tango, mēnā rānei he pai ake ētahi atu rongoā i tērā wā.

  Āhea ka taea e au te whakamutu i te tango i te Lasmiditan?

  Ka taea e koe te whakamutu i te tango i te lasmiditan i ngā wā katoa, nā te mea ehara i te rongoā e hiahia ana kia whakamutua mā te āta haere. I te mea e whakamahia ana mō ngā whakaeke migraine takitahi, kaua mō te ārai i ia rā, kāore he tūponotanga o ngā tohumate whakawātea i te wā e whakamutu ana koe.

  Ka taea e koe te whiriwhiri ki te whakamutu i te whakamahi i te lasmiditan mēnā ka kitea e koe he pai ake ētahi atu rongoā, mēnā ka pā ki a koe ngā pānga taha e raruraru ana, mēnā rānei ka iti ake te auau, te kaha rānei o ō migraine. Ka mutu hoki ētahi tāngata i te wā e tīmata ana rātou i ngā rongoā ārai migraine e whakaiti ana i te hiahia mō ngā rongoā koi.

  I mua i te whakamutu, kōrerohia tō whakatau ki tō tākuta, ina koa kua āwhina te lasmiditan i ō migraine. Ka taea e rātou te āwhina ki te whakarite kei a koe ētahi atu kōwhiringa rongoā e wātea ana, ā, ka tūtohu pea i ētahi atu huarahi ki te whakahaere i tō āhuatanga migraine.

  Ka taea e au te tango i te Lasmiditan me ētahi atu rongoā?

  Ka taea e te Lasmiditan te pā tahi ki ētahi rongoā, nō reira he mea nui ki te kōrero ki tō tākuta mō ngā rongoā katoa i runga i te whakahaunga, ngā rongoā i runga i te kaute, me ngā tāpiringa e tango ana koe. Ka taea e ētahi huinga te whakanui i ngā pānga taha, te whakaiti rānei i te whai huatanga.

  Ka taea e te rongoā te whakanui i ngā pānga whakangā o te waipiro, ngā pire moe, ngā rongoā āwangawanga, me ētahi antidepressant. Ka taea e tēnei huinga te tino pōuri, te whanoke rānei i a koe, e whakanui ana i tō tūponotanga o te hinga, o ngā aitua rānei. Ka tūtohu pea tō tākuta kia karo i ēnei huinga, kia whakatika rānei i ngā inenga.

  Me whakapā tonu ki tō tākuta i mua i te tīmatanga o ngā rongoā hou i te wā e whakamahi ana koe i te lasmiditan. Ka taea e rātou te arotake i ngā pānga ka puta pea, ā, ka āwhina i a koe ki te whakahaere i ō rongoā katoa i runga i te haumaru. Kia mau ki tētahi rārangi whakahōu o ō rongoā katoa hei tiritiri ki ngā tākuta katoa e kite ana koe.