He aha te Tecovirimat: Ngā Whakamahinga, te Inenga, Ngā Pānga Taha me Ētahi Atu

Ko te Tecovirimat he rongoā rongoā antiviral i hangaia hei rongoā i ngā mate pūwhāwhā me te mate mōkihi. Ahakoa kua ngaro te pūwhāwhā i te ao katoa, he mea nui tēnei rongoā hei rongoā tuarua, ā, e whakamahia ana i tēnei wā mō ngā keehi mōkihi ina kore e tika ētahi atu rongoā.

Ka mōhio pea koe ki tēnei rongoā mēnā i kōrerohia e tō tākuta hei rongoā mō te mate poxvirus. Me haere tātou i ngā mea katoa e hiahia ana koe ki te mōhio mō te tecovirimat i roto i ngā kupu māmā, mārama.

He aha te Tecovirimat?

Ko te Tecovirimat he rongoā antiviral e aro ana ki ngā poxviruses pēnei i te pūwhāwhā me te mōkihi. E mahi ana mā te aukati i tētahi pūmua e hiahia ana ēnei huaketo ki te horapa mai i tētahi pūtau ki tētahi atu i tō tinana.

I te tuatahi i hangaia te rongoā hei ārai i te pūwhāwhā, ahakoa kua ngaro tēnei mate i ngā tau tekau ki muri. I tēnei rā, e whakamahia ana ki te rongoā i ngā mate mōkihi, ina koa ki ngā tāngata he tohu kino, he nui rānei te tūponotanga ki ngā raruraru.

He rongoā hou tēnei rongoā i te whakataurite ki ētahi atu rongoā antiviral, i te mea i whakawhiwhia ki te whakaaetanga mai i te FDA i te tau 2018. E kiia ana he rongoā motuhake e rahuitia ana mō ngā āhuatanga motuhake, kaua ki te whakamahi i ia rā.

He aha te Tecovirimat e Whakamahia Ana?

Kua whakaaetia te Tecovirimat hei rongoā i te mate pūwhāwhā i ngā pakeke me ngā tamariki e 3 kirokaramu te taumaha (tata ki te 6.6 pauna). E whakamahia ana hoki i waho o te tapanga hei rongoā i ngā mate mōkihi, ina koa i ētahi āhuatanga mōrearea.

Ka tūtohu pea tō tākuta i te tecovirimat mēnā he mōkihi tōu, ā, ka uru koe ki tētahi o ēnei kāwai: he ngoikore tō pūnaha ārai mate, e hapū ana koe, e whāngai ū ana koe, he tohu kino rānei ōu. Ka whakaarohia pea te rongoā mō ngā tāngata he mate kiri pēnei i te eczema, i te mea ka nui ake te tūponotanga ki ngā raruraru.

Ahakoa ka taea te whakamahi i te tecovirimat mō ētahi atu mate poxvirus, he tino onge ēnei āhuatanga. Ko te nuinga o te hunga e pangia ana e te monkeypox ka ora me te kore e hiahia ki te rongoā antiviral, nā reira ka rahuitia tēnei rongoā mō ngā tūāhuatanga e hiahiatia ana he tautoko anō.

Me pēhea te mahi a Tecovirimat?

Ka mahi te Tecovirimat mā te whai i tētahi pūmua motuhake e kiia nei ko VP37 e hiahia ana ngā poxvirus ki te horapa puta noa i tō tinana. Whakaarohia me te mea kei te aukati koe i tētahi kī e whakamahia ana e te huaketo hei iriti i ngā tatau i waenga i ngā pūtau.

Inā tangohia e koe te tecovirimat, ka ārai i te huaketo mai i te pōkai tika i a ia anō me te neke mai i ngā pūtau kua pangia ki ngā pūtau hauora. Kāore tēnei e patu tika i te huaketo, engari ka whakaroa nui i tōna kaha ki te horapa me te whara anō.

E kiia ana he kaha te rongoā i waenga i ngā rongoā antiviral. He mea hanga motuhake mō ngā poxvirus, e tino whai ana i te whāinga engari ko te tikanga hoki kāore e mahi ki ētahi atu momo mate viral pērā i te rewharewha, i te makariri noa rānei.

Me pēhea taku tango i te Tecovirimat?

Tangohia te tecovirimat kia rite ki te tohutohu a tō tākuta, te tikanga e rua ngā wā i ia rā me te kai. Ka pai te mahi a te rongoā inā tangohia me te kai kei roto ētahi ngako, nā te mea ka āwhina tēnei i tō tinana ki te ngongo i te rongoā.

Me tango e koe ia horopeta tata ki te 12 hāora te wehenga, nā reira ki te tango koe i tō horopeta tuatahi i te 8 AM me te parakuihi, tangohia tō horopeta tuarua i te 8 PM me te kai tina. Whakamātauria ki te kai i tētahi mea nui me ia horopeta kaua ki te kai paramanawa noa.

Horomia ngā kāpene katoa me te wai. Kaua e kuru, e ngaungau, e whakatuwhera rānei, nā te mea ka pā tēnei ki te mahi a te rongoā. Ki te raru koe ki te horomia i ngā kāpene, kōrero ki tō tākuta mō ētahi atu kōwhiringa.

Haere tonu ki te tango i te rongoā mō te akoranga katoa e tohutohutia ana e tō tākuta, ahakoa ka tīmata koe ki te pai ake. Ko te whakamutu wawe ka taea e te huaketo te hoki mai anō.

Kia pēhea te roa e tango ai au i te Tecovirimat?

Ko te akoranga noa o te tecovirimat e 14 ra te roa, engari tera pea ka whakatikatikaina e to tākuta i runga i tō āhuatanga. Ko te nuinga o te tangata e tango ana i te rongoa nei mō ngā wiki e rua, e rua ngā kapene i ia rā.

Ka whakatau tō tākuta i te roa tika i runga i ētahi mea: te kaha o tō mate, te pēhea o te mahi o tō pūnaha ārai mate, me te pēhea o tō urupare ki te rongoā. Tera pea ka hiahia ētahi tāngata i tētahi akoranga poto ake, i te wā e hiahia ana ētahi atu i tētahi rongoā roa ake.

Kaua e mutu te tango i te tecovirimat i mua i te wā, ahakoa ka pai ake ō tohumate. He uaua ngā mate poxvirus, ā, ko te whakamutu i te rongoā i te wā wawe rawa pea ka hoki mai te mate, ka kaha ake rānei.

He aha ngā pānga taha o te Tecovirimat?

He pai te whakamanawanui o te nuinga o te tāngata ki te tecovirimat, engari pērā i ngā rongoā katoa, ka pānga taha pea. Ko te rongo pai he mea noa ngā pānga taha nui, ā, ko te nuinga o te tāngata ka pā te tohumate ngawari noa iho, ki te pā rānei.

Koinei ngā pānga taha tino noa ka pā pea ki a koe i te wā e tango ana koe i te tecovirimat:

• Te ānini
• Te whakapairuaki, te pōraruraru puku rānei
• Te mamae o te puku
• Te ruaki
• Te ngenge, te ngenge rānei
• Te whanoke

He ngawari noa iho ēnei tohumate, ā, he maha ngā wā ka pai ake i te wā e urutau ana tō tinana ki te rongoā. Ko te tango i te rongoā me te kai ka āwhina i te whakaiti i ngā pānga taha e pā ana ki te puku.

Ko ngā pānga taha iti noa iho engari he nui ake te kino ka uru pea ki ngā urupare pāwera nui, ahakoa he mea noa ēnei. Whakapā atu ki tō tākuta tonu ki te pā ki a koe te uaua ki te hā, te pupuhi nui, te pupuhi rānei o tō mata, ngā ngutu, te arero, te korokoro rānei.

Tera pea ka pā ki ētahi tāngata ngā huringa i ngā hua o te whakamātautau toto, ina koa e pā ana ki te mahi ate. Tera pea ka aroturukihia ēnei taumata e tō tākuta ki te tango koe i te rongoā mō tētahi wā roa.

Ko wai kāore e tika kia tango i te Tecovirimat?

He pai tonu te Tecovirimat mō te nuinga o te tāngata, engari he wāhi ka kore pea e tika. Ka āta whakaaro tō tākuta ki tō hītori hauora i mua i te whakahau.

Kaua koe e tango tecovirimat mēnā he pānga tōna ki a koe, ki ōna kai rānei. Kōrero ki tō tākuta mō ngā pānga pānga ki ngā rongoā i mua, ina koa kua pā tōna pānga nui ki a koe i mua.

Ko te hunga e mate ate nui ana, tērā pea ka hiahia ki te aroturuki motuhake, ki tētahi atu huarahi rongoā rānei. Ka tukatukahia te rongoā e tō ate, nō reira ka pā te raruraru ate nui ki te pai o tōna mahi, ka piki rānei te tūponotanga o ngā pānga taha.

Mēnā kei te hapū koe, kei te whāngai ū rānei, ka whakataurite tō tākuta i ngā painga ki ngā tūponotanga. Ahakoa ka taea te whakamahi tecovirimat i te wā o te hapū mō ngā mate nui, me āta whakaaro tēnei whakatau ki tō āhuatanga motuhake.

Ingoa Waitohu Tecovirimat

Ka hokona te Tecovirimat i raro i te ingoa waitohu TPOXX i te United States. Koinei anake te ingoa waitohu e wātea ana mō tēnei rongoā, nā te mea kotahi te kamupene e hanga ana.

Tērā pea ka kite koe i te kīia ko ST-246 i ētahi tuhinga rongoā, ko tōna ingoa rangahau i mua i te wātea mai i te hokohoko. Heoi, ka whiwhi koe i tō rongoā, ka tapaina ko TPOXX.

Ka tae mai te rongoā i roto i ngā pūtau 200-milligram, ā, kāore he putanga whānui e wātea ana i tēnei wā. Ko te tikanga ko ngā rongoā tecovirimat katoa ka mō te waitohu TPOXX.

Ngā Kōwhiringa Tecovirimat

I tēnei wā, he iti noa ngā kōwhiringa tika ki te tecovirimat mō te rongoā i ngā mate poxvirus. Ko te kōwhiringa matua ko te cidofovir, he rongoā antiviral tawhito ka taea te whakamahi mō ngā keehi monkeypox nui.

Ka tukuna a Cidofovir mā te uaua (mā te IV) me te hōhipera mō te whakahaere. Ko te tikanga ka whakaarohia i te wā e kore ai e wātea, e tika ana rānei a tecovirimat, engari he nui ake ngā pānga taha, me te aro turuki.

Ko Brincidofovir tētahi atu rongoā pea e rangahaua ana mō ngā mate poxvirus. E pā ana ki a cidofovir engari ka taea te tango mā te waha, ahakoa kāore anō kia wātea whānuitia mō tēnei whakamahinga.

Mō te nuinga o ngā tāngata e pangia ana e te monkeypox, he nui te manaaki tautoko kāore he rongoā antiviral. Kei roto i tēnei te whakahaere i te mamae, te manaaki i ngā patunga, me te aro turuki mō ngā raruraru.

He Pai Anei a Tecovirimat i te Cidofovir?

Ko te tikanga he pai ake a Tecovirimat i te cidofovir mō te nuinga o ngā tāngata e hiahia ana ki te rongoā antiviral mō ngā mate poxvirus. Ko te painga nui ko te mea ka taea te tango a tecovirimat i te kāinga hei kapene waha, i te mea me hōhipera a cidofovir mō te whakahaere IV.

He iti ake hoki ngā pānga taha kino a Tecovirimat i te cidofovir. Ka taea e Cidofovir te whara i te pūkahukahu me ētahi atu raruraru nui, e hiahia ana ki ngā whakamātautau toto auau me te aro turuki i te wā o te rongoā.

Heoi anō, kua roa te whakamahi a cidofovir, ā, he nui ake ngā raraunga mō tōna whai huatanga. I ētahi wā tino kino, ka pai pea ngā tākuta ki te cidofovir ahakoa ōna ngoikoretanga, ina koa kāore te tangata e pai ana ki te tecovirimat.

Ka whiriwhiri tō tākuta i te kōwhiringa pai rawa atu i runga i tō āhuatanga motuhake, me te whakaaro ki ngā āhuatanga pēnei i te kaha o tō mate, tō hauora whānui, me te mea ka taea e koe te tango rongoā waha.

Ngā Pātai Auau Mō Tecovirimat

Q1. He Haumaru Anei a Tecovirimat mō ngā Wāhine Hapū?

Ka taea te whakamahi a Tecovirimat i te wā o te hapū i te wā e nui ake ana ngā painga i ngā tūponotanga, ina koa mō ngā mate poxvirus kino. Kāore anō ngā rangahau kararehe i whakaatu i ngā pānga kino ki te hapū, engari he iti ngā raraunga tangata mai i te mea he rongoā hou te rongoā.

Mēnā kei te hapū koe, ā, he mate huaketo poxvirus tō, ka āta whakataurite tō tākuta i ngā tūponotanga o te mate ki ngā tūponotanga ka puta mai i te rongoā. He mōrearea pea ngā mate poxvirus nui i te wā e hapū ana, nō reira he maha ngā wā e tūtohutia ana te rongoā.

Ka mātakitaki pū tō tākuta i a koe i te wā e rongoatia ana koe mēnā kei te hapū koe. Ko te whakatau ki te whakamahi i te tecovirimat i te wā e hapū ana ka mahia i ia keehi i ia keehi, me te whakaaro ki ō āhuatanga motuhake.

Q2. Me Pēhea Taku Mahi Mēnā Ka Inu Au i te Nui Rawa o te Tecovirimat?

Mēnā ka inu koe i te nui rawa o te tecovirimat i te mea i whakaritea, whakapā atu ki tō tākuta, ki te pokapū whakahaere paitini rānei i te wā tonu. Kaua e tatari kia kite mēnā e pāngia ana koe, he pai ake te tiki tohutohu i te wā tonu.

Ko te inu i te nui rawa o te tecovirimat ka piki ake pea te tūponotanga o ngā pānga taha, ina koa te whakapairuaki, te ruaki, me te mamae o te puku. I ētahi wā, ka pā pea ki te mahi ate, ahakoa he nui ake te tūponotanga ki ngā horopeta nui ake.

I te wā e waea ana koe mō te āwhina, kia rite tō pounamu rongoā kia taea e koe te kōrero ki a rātou te nui tonu i inumia e koe me te wā. Mā rātou koe e ārahi mēnā e hiahia ana koe ki te āwhina hauora tonu, ka taea rānei te mātakitaki i te kāinga.

Q3. Me Pēhea Taku Mahi Mēnā Ka Ngaro Au i te Horopeta o te Tecovirimat?

Mēnā ka ngaro koe i te horopeta o te tecovirimat, tangohia i te wā e mahara ana koe, mena kāore anō kia tata te wā mō tō horopeta e whai ake nei. Mēnā kua neke atu i te 6 hāora mai i tō horopeta i ngaro, ā, kei te tata koe ki tō horopeta i whakaritea e whai ake nei, waiho te horopeta i ngaro, ka haere tonu ki tō hōtaka auau.

Kaua e tango i ngā horopeta e rua i te wā kotahi hei utu mō te horopeta i ngaro, nā te mea ka piki ake pea tō tūponotanga o ngā pānga taha. He pai ake te pupuri i tō hōtaka auau, kaua e rua ngā rongoā.

Whakamātauria te whakatakoto i ngā whakamaharatanga ki tō waea, whakamahia rānei tētahi kaiwhakarite pire hei āwhina i a koe ki te mahara ki ō horopeta. He mea nui te horopeta rite tonu mō te pupuri i te rongoā i ngā taumata whai hua i tō tinana.

Q4. Āhea Ka Taea e Au te Kati te Tango Tecovirimat?

Me mutu anake te tango i te tecovirimat ina korero mai tō tākuta ki a koe, i muri i te whakaoti i te akoranga 14-ra. Kaua e mutu wawe ahakoa ka tino pai koe, na te mea ka taea e te huaketo te hoki ano ki te kaha.

Ka tohutohu pea tō tākuta kia mutu wawe te rongoā mena ka pa ki a koe ngā pānga taha kino, mena rānei ka tere te whakaora o tō mate. Heoi, me whakatau tonu tēnei whakatau e tō kaiwhakarato hauora, kaua e whakatau i a koe anō.

Mena kei te raru koe ki te whakawhiti i te rongoā, kōrero ki tō tākuta mō ō tohu, kaua e mutu i a koe anō. Ka taea pea e rātou te whakatika i tō maimoatanga, te whakarato rānei i te manaaki tautoko hei āwhina i a koe ki te whakaoti i te akoranga.

Q5. Ka taea e au te inu waipiro i te wā e tango ana i te Tecovirimat?

He pai ake te karo i te waipiro i te wā e tango ana i te tecovirimat, ina koa kei te pā koe i te puku, te whakapairuaki rānei i te rongoā. Ka taea e te waipiro te whakapōrearea i ēnei pānga taha, ā, ka raru pea i tō whakaora.

Ahakoa kāore he pānga kino motuhake i waenga i te tecovirimat me te waipiro, ka taea e te inu te whakanui i te pēhanga ki tō ate, e tātari ana i te rongoā. He mea nui tēnei ina he raruraru ate tō.

Aronga ki te noho pai te wai ki te wai me ētahi atu inu kore-waipiro i te wā e ora ana koe i tō mate. E hiahia ana tō tinana i ōna rauemi katoa ki te whawhai i te huaketo me te whakaora tika.